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Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2

✍ Scribed by A. M. KERRIGAN; L. NAVARRO-NUÑEZ; E. PYZ; B. A. FINNEY; J. A. WILLMENT; S. P. WATSON; G. D. BROWN


Book ID
114754660
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
228 KB
Volume
10
Category
Article
ISSN
1538-7933

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## Abstract Thrombin levels increase at sites of vascular injury and during acute coronary syndromes. It is also increased several fold by sepsis with a reciprocal decrease in the anti‐thrombin III levels. In this study we investigate the effects of thrombin on the induction of cyclooxygenase‐2 (CO