Podocarpic Acid Derivatives. Synthesis of Nimbiol
β Scribed by Wenkert, Ernest; Stenberg, Virgil I.; Beak, Peter
- Book ID
- 127170256
- Publisher
- American Chemical Society
- Year
- 1961
- Tongue
- English
- Weight
- 858 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
NIMBIOL' , a compound isolated from the trunk bark of Melia azadirachta Lilln., has been assigned 2-3 the structure Ia. Ia. R=H b. R=CHs We have converted podocarpic acid to compounds having structures Ia and Ib and have found them to be identical with nimbi01 and nimbi01 methyl ether1 thus confirmi
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One of the foremest problems encountered in synthesis of diterpenoid resin acids is that of stereoselective introduction of methyl and carboxyl substituents at the quaternary k-position in the correct configuration relative to the C-10 angular methyl. Most previous syntheses