POD-09.04: Lack of Androgen Regulation of PDE5 Expression
โ Scribed by R. Yang; Y. Huang; G. Lin; G. Wang; S. Hung; Y. Dai; H. Guo; Z. Sun; T. Lue; C. Lin
- Book ID
- 118502875
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 124 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0090-4295
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Androgen receptors are important transcription factors regulating the expression of a number of genes in androgen-responsive cells and may play a role in prostate cancer. This article describes transcriptional suppressors and other transcription factors which may play important roles in modulating t
## BACKGROUND. The growth and function the normal prostate is dependent on the presence of androgen. As prostate tumors progress there is a loss of androgen-dependent cell growth. The identification of the genes that are regulated by androgens may be of pathological and clinical significance. METH