POD-03.07: High tumor expression of KI-67 is an independent predictor of poor outcome among patients treated surgicaly for clear cell renal cell carcinoma

Ki-67 and coagulative tumor necrosis are

Ki-67 and coagulative tumor necrosis are independent predictors of poor outcome for patients with clear cell renal cell carcinoma and not surrogates for each other

✍ Matthew K. Tollefson; R. Houston Thompson; Yuri Sheinin; Christine M. Lohse; Joh 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 146 KB 👁 2 views

## Abstract ## BACKGROUND. Ki‐67 is a cell proliferation protein associated with aggressive clear cell renal cell carcinoma (ccRCC). A recent report suggests that Ki‐67 may represent a surrogate marker for coagulative tumor necrosis. Thus, the goal was to directly test whether Ki‐67 and necrosis c