Pocket Guide to Biomolecular NMR

✍ Scribed by Michaeleen Doucleff, Mary Hatcher-Skeers, Nicole J. Crane (auth.)

• Publisher: Springer-Verlag Berlin Heidelberg
• Year: 2011
• Tongue: English
• Leaves: 172
• Edition: 1
• Category: Library

✦ Synopsis

Steering clear of quantum mechanics and product operators, "Pocket Guide to Biomolecular NMR" uses intuitive, concrete analogies to explain the theory required to understand NMR studies on the structure and dynamics of biological macromolecules. For example, instead of explaining nuclear spin with angular momentum equations or Hamiltonians, the books describes nuclei as "bells" in a choir, ringing at specific frequencies depending on the atom type and their surrounding electromagnetic environment.This simple bell analogy, which is employed throughout the book, has never been used to explain NMR and makes it surprisingly easy to learn complex, bewildering NMR concepts, such as dipole-dipole coupling and CPMG pulse sequences. Other topics covered include the basics of multi-dimensional NMR, relaxation theory, and Model Free analysis. The small size and fast pace of “Pocket Guide to Biomolecular NMR” makes the book a perfect companion to traditional biophysics and biochemistry textbooks, but the book's unique perspective will provide even seasoned spectroscopists with new insights and handy “thought” short-cuts.

✦ Table of Contents

Front Matter....Pages i-xi
Atomic Bells and Frequency Finders....Pages 1-18
Bonded Bells and Two-Dimensional Spectra....Pages 19-42
Neighboring Bells and Structure Bundles....Pages 43-73
Silencing of the Bells: Relaxation Theory Part One....Pages 75-105
Relaxation Theory Part Two: Moving Atoms and Changing Notes....Pages 107-129
Protein Dynamics....Pages 131-156
Back Matter....Pages 157-159

✦ Subjects

Biochemistry, general;Spectroscopy/Spectrometry;Biophysics and Biological Physics;Molecular Medicine