PO-09 Expression of alternatively spliced tissue factor in human endothelial cells: induction by inflammatory stimuli and modulation by heparins

Induction of interleukin-1 and subsequen

Induction of interleukin-1 and subsequent tissue factor expression by anti-proteinase 3 antibodies in human umbilical vein endothelial cells

✍ Michel de Bandt; Véronique Ollivier; Catherine Babin-Chevaye; Fouzi Khechaï; Dom 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 980 KB

## Objective: To assess the ability of anti-proteinase 3 (anti-pr3) classic antineutrophil cytoplasmic antibodies (canca) to stimulate endothelial expression of tissue factor (tf), which is the main initiator of the coagulation cascade that can lead to endothelial injury and thrombosis in patients