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PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes

✍ Scribed by Jean M. Petit; Boris Guiu; David Masson; Laurence Duvillard; Valerie Jooste; Perrine Buffier; Benjamin Bouillet; Marie-Claude Brindisi; Isabelle Robin; Philippe Gambert; Bruno Verges; Jean-Pierre Cercueil; Patrick Hillon

Book ID
111239575
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
136 KB
Volume
31
Category
Article
ISSN
0106-9543

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Inherited factors play a major role in the predisposition to nonalcoholic fatty liver disease (NAFLD), and the rs738409 CfiG polymorphism of PNPLA3/adiponutrin, encoding for the isoleucine-to-methionine substitution at residue 148 (I148M) protein variant, has recently been recognized as a major dete