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PML tumor suppressor protein is required for HCV production

✍ Scribed by Kuroki, Misao; Ariumi, Yasuo; Hijikata, Makoto; Ikeda, Masanori; Dansako, Hiromichi; Wakita, Takaji; Shimotohno, Kunitada; Kato, Nobuyuki

Book ID
120945591
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
815 KB
Volume
430
Category
Article
ISSN
0006-291X

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## Abstract Parafibromin, encoded by the gene __HRPT2__, is a tumor suppressor protein associated with the RNA polymerase II‐associated complex, Paf1 complex. __HRPT2__ mutations were first identified in patients with the multiple endocrine neoplasia syndrome, hyperparathyroidism‐jaw tumor (HPT‐JT)