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PM10 impairs the antioxidant defense system and exacerbates oxidative stress driven cell death

✍ Scribed by Yolanda I. Chirino; Yesennia Sánchez-Pérez; Álvaro R. Osornio-Vargas; Rocío Morales-Bárcenas; María Concepción Gutiérrez-Ruíz; Yazmin Segura-García; Irma Rosas; José Pedraza-Chaverri; Claudia M. García-Cuellar

Book ID
119381838
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
784 KB
Volume
193
Category
Article
ISSN
0378-4274

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## Abstract Neuronal death, attributable to perturbed redox homeostasis, is the underlying factor in many acute and chronic neurological disorders. The mechanisms employed by oxidatively stressed neurons to commit to cell death pathways are beginning to be characterized, but this is hampered by a l