Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development
β Scribed by Richard P. Davis; Cathelijne W. van den Berg; Simona Casini; Stefan R. Braam; Christine L. Mummery
- Book ID
- 116758340
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 801 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1471-4914
No coin nor oath required. For personal study only.
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## Abstract Considerable hope surrounds the use of diseaseβspecific pluripotent stem cells to generate models of human disease allowing exploration of pathological mechanisms and search for new treatments. Diseaseβspecific human embryonic stem cells were the first to provide a useful source for stu
## Abstract The derivation of embryonic stem cells (hESC) from human embryos a decade ago started a new era in perspectives for cell therapy as well as understanding human development and disease. More recently, reprogramming of somatic cells to an embryonic stem cellβlike state (induced pluripoten