Pluripotent stem cell for modeling neurological diseases
β Scribed by Yung, Jasmine Sum-Yee; Tam, Paul Kwong-Hang; Ngan, Elly Sau-Wai
- Book ID
- 118506494
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 525 KB
- Volume
- 319
- Category
- Article
- ISSN
- 0014-4827
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In the past few years, cellular programming, whereby virtually all human cell types, including those deep within the brain or internal organs, can potentially be produced and propagated indefinitely in culture, has opened the door to a new type of disease modeling. Importantly, many diseases or dise
## Abstract Considerable hope surrounds the use of diseaseβspecific pluripotent stem cells to generate models of human disease allowing exploration of pathological mechanisms and search for new treatments. Diseaseβspecific human embryonic stem cells were the first to provide a useful source for stu