Plenary Session IV: Industrial/Academic Collaboration to Find Genes and Update on Genes for Alzheimer's Disorder
✍ Scribed by Curry, Cynthia J.; Stevenson, Roger E.; Aughton, David; Byrne, Janice; Carey, John C.; Cassidy, Suzanne; Cunniff, Christopher; Graham, John M.; Jones, Marilyn C.; Kaback, Michael M.; Moeschler, John; Schaefer, G. Bradley; Schwartz, Stuart; Tarleton, Jack; Opitz, John
- Book ID
- 101210319
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 66 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
✦ Synopsis
The discovery and development of new drugs is an inherently risky endeavor with historically high attrition rates, a relatively low probability of technical success and (not suprising) astronomically high costs. However, revolutionary advances in biology and chemistry have created an unprecedented environment for new drug discoveryparticularly in our ability to identify and validate biological targets as well as to find small molecule ligands or modulators selective for these targets. Genomics, especially functional genomics, allows pharmaceutical scientists to understand disease processes at their most fundamental level(s) and, therefore, to potentially intervene in a relatively definitive fashion. In this presentation, I will