The acetamidase of Aspergillus nidulans is induced by sources of acetyl CoA, benzoate and benzamide and by beta-alanine and other omega-amino acids. The effects of these groups of inducers are appromimately additive. The cis-acting control site mutant, amdI9, affects induction by sources of acetyl-C
Pleiotropic mutants affecting the control of nitrogen metabolism in Aspergillus nidulans
โ Scribed by Hynes, M. J.
- Publisher
- Springer
- Year
- 1973
- Tongue
- English
- Weight
- 589 KB
- Volume
- 125
- Category
- Article
- ISSN
- 0026-8925
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The creA204, creB15 and creC27 mutations have been shown to cause carbon catabolite derepression of acetly CoA synthase and isocitrate lyase in Aspergillus nidulans. A recessive mutation, cre-34, which is linked to the creC gene, results in these enzymes being more sensitive than cre or wildtype str
Mutants, designated tamAr, have been isolated on the basis of simultaneous resistance to toxic analogues thiourea, aspartate hydroxamate and chlorate with L-alanine as the sole nitrogen source. tamAr mutants are also resistant to methylammonium. This resistance of tamAr mutants is correlated with pa