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Pleiotropic Effects of a Schweinfurthin on Isoprenoid Homeostasis

✍ Scribed by Sarah A. Holstein; Craig H. Kuder; Huaxiang Tong; Raymond J. Hohl

Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
660 KB
Volume
46
Category
Article
ISSN
0024-4201

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## Abstract Hyperlipidemia is frequently associated with insulin resistance states as found in type 2 diabetes and obesity. Effects of free fatty acids (FFA) on pancreatic β‐cells have long been recognized. Acute exposure of the pancreatic β‐cell to FFA results in an increase of insulin release, wh