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PLC-dependent intracellular Ca2+ release was associated with C6-ceramide-induced inhibition of Na+ current in rat granule cells

✍ Scribed by Zheng Liu; Xiao-Wei Fei; Yan-Jia Fang; Wen-Jie Shi; Yu-Qiu Zhang; Yan-Ai Mei


Book ID
111181027
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
683 KB
Volume
106
Category
Article
ISSN
0022-3042

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C6-ceramide inhibited Na+ currents by in
✍ Zheng Liu; Jian-Guang Xu; Hua Zhang; Yan-Jia Fang; Yan-Ai Mei πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 517 KB

## Abstract Ceramides are novel second messengers that may mediate signaling leading to apoptosis and the regulation of cell cycle progression. Moreover, ceramide analogs have been reported to directly modulate K^+^ and Ca^2+^ channels in different cell types. In this report, the effect of C~6~‐cer