Platinum supported on TiO2 as a new selective catalyst on heterogeneous hydrogenation of α,β-unsaturated oxosteroids

✍ Scribed by Rui M.D. Nunes; Bruno F. Machado; Mariette M. Pereira; Maria José S.M. Moreno; Joaquim L. Faria

• Publisher: Elsevier Science
• Year: 2010
• Tongue: English
• Weight: 427 KB
• Volume: 333
• Category: Article
• ISSN: 1381-1169
• DOI: 10.1016/j.molcata.2010.09.019

✦ Synopsis

This paper describes the photochemical deposition of platinum onto TiO 2 surface and the full characterization of the catalysts using BET, XPS and TEM techniques. The 1 and 3 wt. % Pt/TiO 2 catalysts reveal high activity with 70% and 96% of ␣-diastereoselectivity in the hydrogenation of the carbon-carbon double bond of the ␣,␤-unsaturated oxosteroids 4-androstene-3,17-dione, and 3␤-acetoxypregna-5,16-dien-20one, respectively. Using higher temperature and pressure, the catalysts promote the further reduction of C-3 carbonyl group. Catalyst recovering and recycling is easily achieved with no appreciable lost of catalytic activity after five subsequent runs.