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Platelets in Tumor Progression: A Host Factor That Offers Multiple Potential Targets in the Treatment of Cancer

✍ Scribed by Sharma, Deva; Brummel-Ziedins, Kathleen E.; Bouchard, Beth A.; Holmes, Chris E.

Book ID
125480085
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
863 KB
Volume
229
Category
Article
ISSN
0021-9541

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## Abstract Despite the fact that expression of Fas ligand (FasL) in cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells plays an important role in Fas‐mediated tumor killing, During tumor progression FasL‐expressing tumor cells are involved in __counterattacking__ to kill tumor‐infiltr