'a Rapid Increase In Our Understanding Of The Biology Of Platelets And Their Role In Disease In Recent Years Has Been Paralleled By Increasing Successes With Established Platelet-modifying Therapies In Many Clinical Conditions. This Text Focuses On The Clinical Role Of Platelets In A Wide Variety Of Hematologic, Cardiovascular And Other Disorders, Providing A Practical, Clinically Relevant Handbook For All Clinicians And Researchers Interested In Platelets And Their Role In Disease. Covering Platelet Physiology, Bleeding Disorders, Thrombotic Disorders And Antithrombotic Therapy. Chapters Cover All The Conventional And Less Conventional Aspects Of Platelet Involvement In Disease, With An Emphasis On Recent Clinical Developments. Clear Take Home Messages Have Been Included In Each Chapter To Aid Clinical Practice. With Contributions From Leading Experts Across Three Continents, Platelets In Hematologic And Cardiovascular Disorders Is An Up-to-date, Well Illustrated, Practical Resource For Everyone Involved In Clinical Practice With Platelet Disorders.'--back Cover. 1. The Structure And Production Of Blood Platelets / Joseph E. Italiano, Jr. -- 2. Platelet Immunology: Structure, Functions, And Polymorphisms Of Membrane Glycoproteins / Yasuo Ikeda, Yumiko Matsubara And Tetsuji Kamata -- 3. Mechanisms Of Platelet Activation / Lawrence Brass And Timothy J. Stalker -- 4. Platelet Priming / Paolo Gresele, Emanuela Falcinelli And Stefania Momi -- 5. Platelets And Coagulation / Jose A. Lopez And Ian Del Conde -- 6. Vessel Wall-derived Substances Affecting Platelets / Azad Raiesdana And Joseph Loscalzo -- 7. Platelet-leukocyte-endothelium Cross Talk / Kevin J. Croce, Masashi Sakuma And Daniel L. Simon -- 8. Laboratory Investigation Of Platelets / Eduard Shantsila, Timothy Watson And Gregory Y. H. Lip -- 9. Clinical Approach To The Bleeding Patient / Jos Vermylen And Kathelijne Peerback -- 10. Thrombocytopenia / James B. Bussel And Andrea Primiani -- 11. Reactive And Clonal Thrombocytosis / Ayalew Telieri -- 12. Congenital Disorders Of Platelet Function / Marco Cattaneo -- 13. Acquired Disorders Of Platelet Function / Michael H. Kroll And Amy A. Hassan -- 14. Platelet Transfusion Therapy / Sherrill J. Slichter And Ronald G. Strauss -- 15. Clinical Approach To The Patient With Thrombosis / Brian G. Choi And Valentin Fuster -- 16. Pathophysiology Of Arterial Thrombosis / Juan Jose Badimon, Borja Ibanez And Gemma Vilahur -- 17. Platelets And Atherosclerosis / Stephan Lindemann And Meinrad Gawaz -- 18. Platelets In Other Thrombotic Conditions / David L. Green, Peter W. Marks And Simon Karpatkin -- 19. Platelets In Respiratory Disorders And Inflammatory Conditions / Paolo Gresele, Stefania Momi, Simon C. Pitchford And Clive P. Page -- 20. Platelet Pharmacology / Dermot Cox -- 21. Antiplatelet Therapy Versus Other Antithrombotic Strategies / Nicolas Mejevoi, Catalin Doiangiu And Marc Cohen -- 22. Laboratory Monitoring Of Antiplatelet Therapy / Paul Harrison And David Keeling -- 23. Antiplatelet Therapies In Cardiology / Peirluigi Tricori And Robert A. Harrington -- 24. Antithrombotic Therapy In Cerebrovascular Disease / James Castle And Gregory W. Albers -- 25. Antiplatelet Treatment In Peripheral Arterial Disease / Raymond Verhaeghe And Peter Verhamme -- 26. Antiplatelet Treatment Of Venous Thromboembolism / Menno Y. Huisman, Jaapjan D. Snoep, Jouke T. Tamsnia And Marcel M. C. Hovens. Edited By Paolo Gresele ... [et Al.]. Includes Bibliographical References And Index.