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Platelets as versatile regulators of cutaneous inflammation

✍ Scribed by Katoh, Norito


Book ID
119293412
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
478 KB
Volume
53
Category
Article
ISSN
0923-1811

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Regulation of platelet heparanase during
✍ Nathan S. Ihrcke; William Parker; Kathryn J. Reissner; Jeffrey L. Platt πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 296 KB

Heparan sulfate is rapidly degraded by an endoglycosidase (heparanase) secreted by activated platelets. Since the cleavage and release of heparan sulfate would profoundly alter the local physiology of the endothelium, platelet heparanase activity should be tightly regulated. Consistent with this hyp