Plateletpheresis: A comparative study of six different protocols

✍ Scribed by Dr. Li. Puig; R. Mazzara; A. Gelabert; R. Castillo

• Publisher: John Wiley and Sons
• Year: 1986
• Tongue: English
• Weight: 337 KB
• Volume: 3
• Category: Article
• ISSN: 0733-2459
• DOI: 10.1002/jca.2920030210

✦ Synopsis

Six different protocols were employed in 710 plateletpheresis employing Haemonetics 30. Fenwal CS-3000, IBM 2997 dual stage channel, ISM 2997 single-stage channel, and Haemonetics V-50 "surge pump" method. When Haemonetics 30 and IBM 2997 single-stage channel procedures were used, 5.4 to 5.9 X 10" platelets were collected with significant leukocyte contamination (10.8 to 11.6 X lo9). With Fenwal CS-3000, dual-stage channel of IBM 2997 and Haemonetics V-50 "surge pump" there was less leukocyte contamination in concentrates (0.3 to 0.9 X 10' ) as well as a lower platelet yield (3.4 to 4.3 X 10"). No difference in yield was observed when plateletpheresis was performed with ACD-A or ACD-B employing the single-stage channel of IBM 2997. Paraesthesias was the most frequently seen side effect in donors. with a higher incidence when using ACD-A and IBM 2997.