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Platelet-type 12-lipoxygenase activates NF-κB in prostate cancer cells

✍ Scribed by Mustapha Kandouz; Daotai Nie; Graham P Pidgeon; Sriram Krishnamoorthy; Krishna Rao Maddipati; Kenneth V Honn

Book ID
114365633
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
266 KB
Volume
71
Category
Article
ISSN
0090-6980

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## Abstract The NF‐κB family of transcription factors has been shown to be constitutively activated in various human malignancies, including leukemias, lymphomas, and a number of solid tumors. NF‐κB is hypothesized to contribute to development and/or progression of malignancy by regulating the expr