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Platelet-rich plasma stimulates cytokine expression and alkaline phosphatase activity in osteoblast-derived osteosarcoma cells

โœ Scribed by Bruno S. Herrera; Leila S. Coimbra; Alliny S. Bastos; Simone A. Teixeira; Joao P. Steffens; Marcelo N. Muscara; Luis C. Spolidorio


Book ID
118416437
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
585 KB
Volume
57
Category
Article
ISSN
0003-9969

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โœ Shoukat Dedhar ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 1016 KB

Recombinant human interleukin-1 beta, a mediator of osteoblastic cell function, was found to regulate the expression of the cell adhesion receptors, integrins, on human osteosarcoma cells. Interleukin-1 beta (IL-1 beta) at picomolar concentrations, specifically elevated approximately six- to tenfold