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Platelet polyphosphate: an endogenous activator of coagulation factor XII

✍ Scribed by N. MACKMAN; A. GRUBER


Book ID
109153305
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
115 KB
Volume
8
Category
Article
ISSN
1538-7933

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## Abstract Activation of human blood plasma coagulation by contact with hydrophilic or hydrophobic surfaces (procoagulants) is dominated by kallikrein (Kal)‐mediated activation of the blood zymogen FXII (Hageman Factor). Mathematical modeling of prekallikrein (PK)‐deficient platelet‐poor plasma (d