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Platelet glycoprotein IIb/IIIa receptor blockade therapy for large coronary aneurysms and thrombi in Kawasaki disease

✍ Scribed by Etheridge, Susan P. ;Tani, Lloyd Y. ;Minich, L. LuAnn ;Revenaugh, James R.

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 246 KB
Volume: 45
Category: Article
ISSN: 0098-6569
DOI: 10.1002/(sici)1097-0304(199811)45:3<264::aid-ccd10>3.0.co;2-2

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✦ Synopsis

A 4-month-old girl with Kawasaki disease, large coronary artery aneurysms, and coronary thrombi was treated with standard therapy followed by abciximab, a platelet glycoprotein IIb/IIIa antagonist, in addition to standard heparin and warfarin sodium anticoagulation and low-dose aspirin. She did not develop evidence of ischemia, had no complications from the therapy, and showed resolution of the aneurysms and thrombi after 6 wk of therapy.

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