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Platelet-derived sphingosine 1-phosphate induces contraction of coronary artery smooth muscle cells via S1P2

✍ Scribed by T. Ohmori; Y. Yatomi; M. Osada; Y. Ozaki


Book ID
109148753
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
216 KB
Volume
2
Category
Article
ISSN
1538-7933

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## Abstract Sphingosine 1‐phosphate (S1P) has been shown to regulate smooth muscle cell proliferation, migration, and vascular maturation. S1P increases the expression of several proteins including COX‐2 in vascular smooth muscle cells (VSMCs) and contributes to arteriosclerosis. However, the mecha