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Platelet-derived growth factor rather than basic fibroblast growth factor and vascular endothelial cell growth factor is involved in adventitial narrowing causing vascular stenosis in end-stage cardiac allograft vasculopathy

✍ Scribed by R.R Meliss; K Pethig; G Steinhoff; W Harringer; B Heublein; H Choritz; A Haverich

Book ID: 117237271
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 48 KB
Volume: 31
Category: Article
ISSN: 0041-1345
DOI: 10.1016/s0041-1345(98)01450-x

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## Abstract We examined the effects of basic fibroblast growth factor (bFGF) and platelet‐derived growth factor (PDGF) on the migration of vascular adventitial fibroblasts (VAFs) isolated from rat aortic adventitiae. Both bFGF and PDGF significantly stimulated VAF migration in vitro. An antibody to