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Platelet adhesion onto sulfonated artificial red blood cells

✍ Scribed by Muramatsu, Nobuhiro ;Kondo, Tamotsu

Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
479 KB
Volume
15
Category
Article
ISSN
0021-9304

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✦ Synopsis

Abstract

Rabbit hemolysate‐loaded microcapsules having sulfonic acid groups on their surface were prepared and rabbit platelet adhesion onto the sulfonated surface was examined kinetically. Rabbit platelets adhered more markedly onto the surface of a higher charge density than that of a lower one, indicating a trend similar to that found in the case of the surface having carboxyl groups. Moreover, the platelets were found to be stickier in the buffer solution than in the plasma, though the dependence of platelet adhesion in the buffer solution on the magnitude of surface charge of the sulfonated artificial red blood cells was still recognized.

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