## Abstract The loss of dopaminergic neurons in the substantia nigra provokes a plasticity of corticostriatal synapses in Parkinson's disease (PD). The corticostriatal pathway nevertheless makes synapses with neurons bearing D1 dopamine receptors (D1R) and/or D2 dopamine receptors. At the ultrastru
β¦ LIBER β¦
Plasticity of nerve afferents to nigrostriatal neurons in parkinson's disease
β Scribed by Philippe Anglade; France Javoy-Agid; Yves AgidM; Etienne C. Hirsch; Shigeru Tsuji
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 896 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0364-5134
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## Abstract Neuronal properties of the human globus pallidus (GP) are not known. Since GP is the major output of the basal ganglia, it may be involved in the pathophysiology of Parkinson's disease. We studied 12 patients with medically resistant Parkinson's disease by using single cell recording of