“Plastic Trash goes Biohybrid”—Rapid and Selective Functionalization of Inert Plastic Surfaces with Biomolecules
✍ Scribed by Stefan M. Schiller; Dev Kambhampati; Gudrun Stengel; Jürgen Dolderer; Peter E. Nielsen; Renate Förch; W. Knoll
- Book ID
- 102488701
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 440 KB
- Volume
- 211
- Category
- Article
- ISSN
- 1022-1352
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The covalent functionalization of “inert” polymers such as polypropylene with biomolecules for biocompatible or biosensor surfaces is challenging. Here we present a powerful approach to covalently modify “inert” macromolecular surfaces with biomacromolecules reusing old plastic material. A special emphasis was placed on easily accessible materials and a process which is easy, fast, efficient, cheap, and reliable. “Plastic trash” (lids from Eppendorf® pipet tip containers) was used as a polymer substrate to demonstrate the use/reuse of commercial packing material to covalently modify this material with a thin reactive plasma polymerized maleic anhydride nanolayer network, which can be subsequently modified with biomolecules for various applications, e.g., in tissue engineering and as biochips.
magnified image