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Plasmonics nanoprobes: detection of single-nucleotide polymorphisms in the breast cancer BRCA1 gene

✍ Scribed by Musundi B. Wabuyele; Fei Yan; Tuan Vo-Dinh

Publisher
Springer
Year
2010
Tongue
English
Weight
547 KB
Volume
398
Category
Article
ISSN
1618-2650

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## Abstract Germline mutations in the BRCA1 and BRCA2 genes are associated with a significantly increased lifetime risk for developing breast and/or ovarian cancer. However, incomplete penetrance and substantial variability in age of disease onset among carriers of the same mutation suggests the in