Plasminogen activator inhibitors in endometrial adenocarcinoma
β Scribed by Noreen C. Gleeson; Rohini Gonsalves; J. Bonnar
- Book ID
- 101333283
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 277 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0008-543X
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Urokinase plasminogen activator (uPA) is a serine protease involved in cancer invasion and metastasis. uPA mediates its action while attached to a membrane-bound receptor (uPAR). In this investigation we show that uPAR levels correlate with uPA levels in human breast cancers. uPAR levels, however, d
## Background: The plasminogen activator system plays an important role in different malignant tumors. these enzymes participate in the destruction of intercellular matrices and basement membranes and/or can modulate the growth potency of tumor cells and may even promote metastases. in this study,