Plasminogen activator activity in clonogenic cell populations separated from a murine fibrosarcoma
β Scribed by Biserka Nagy; David J. Grdina
- Book ID
- 105309013
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 464 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0262-0898
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## Abstract In order to investigate the possible correlation between plasminogen activator (PA) activity and metastatic potential of tumour cells, we studied cultured cells from the murine fibrosarcoma mFS6 and from its two sublines M~4~ and M~9~ which differ markedly in their capacity to cause spo
Elevated levels of plasminogen activator (PA) activity have been correlated with neoplasia and may have an important role in tumor-cell invasion and metastasis. We have developed a new caseinolytic assay that uses an immunochemical approach to measure the activity of PA elaborated by malignant tumor