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Plasmin-induced smooth muscle cell proliferation requires epidermal growth factor activation through an extracellular pathway

โœ Scribed by Elisa Roztocil; Suzanne M. Nicholl; Irfan I. Galaria; Mark G. Davies


Book ID
113920120
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
380 KB
Volume
138
Category
Article
ISSN
0039-6060

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Smooth muscle cell (SMC) hyperplasia is an important component of vascular remodeling in chronic hypoxic pulmonary hypertension. The mechanisms underlying SMC proliferation in the remodeling process are poorly understood, but may involve insulin-like growth factor I (ICF-I). This study investigates