Plasmapheresis in multiple sclerosis
โ Scribed by Bruce C. McLeod
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 64 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0733-2459
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๐ SIMILAR VOLUMES
Acute multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). As listed in Table I, the lesions (plaques) are infiltrated first by perivascular and then by parenchymal T lymphocytes with a CD4' over CD8' cell type pre-Address reprint requests to
Plasmapheresis as a treatment for multiple sclerosis (MS) has been a subject of controversy since its original use in this disorder in 1979 11-31. The rationale for the use of plasmapheresis is that MS presumably is an autoimmune disease with evidence for the presence of anti-myelin antibodies 14-61
The rationale for the use of interferon (IFN) in the treatment of multiple sclerosis (MS) is based on its recognized antiviral and irnmunomodulating actions. The pathogenesis of MS is believed to be due to an immunologic response in a genetically predisposed individual, localized within the central
Interferons (IFN) are biological molecules with antiviral, antiproliferative, and immunomodulatory actions. Plasmapheresis (PP) combined with IFN therapy in 24 multiple sclerosis (MS) patients was associated with a rapid increase in detectable IFN levels. We describe the presence of a detectable fac