๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Plasmapheresis in lupus nephritis with nephrotic syndrome: A long-term followup

โœ Scribed by Daniel J. Wallace; Dennis Goldfinger; Rodney Bluestone; James R. Klinenberg

Book ID
102296723
Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
329 KB
Volume
1
Category
Article
ISSN
0733-2459

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โœฆ Synopsis

Abstract

Lupus nephritis with nephrotic syndrome is one of the most serious complications of systemic lupus erythematosus. Six female patients with systemic lupus and nephrotic syndrome, refractory to immunosuppressive drug therapy, received 15โ€“20 exchange plasmaphereses. One patient, treated concurrently with highโ€dose steroids, showed temporary improvement, and five patients, treated concurrently with steroids and either cyclophosphamide or azathioprine, had longโ€term remissions. Plasmapheresis is a promising therapeutic modality in cases of refractory lupus nephritis with nephrotic syndrome.

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โœ Frรฉdรฉric A. Houssiau; Carlos Vasconcelos; David D'Cruz; Gian Domenico Sebastiani ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 82 KB ๐Ÿ‘ 2 views

## Abstract ## Objective In the Euroโ€Lupus Nephritis Trial (ELNT), 90 patients with lupus nephritis were randomly assigned to a highโ€dose intravenous cyclophosphamide (IV CYC) regimen (6 monthly pulses and 2 quarterly pulses with escalating doses) or a lowโ€dose IV CYC regimen (6 pulses of 500 mg g