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Plasmapheresis in acute disseminated encephalomyelitis

✍ Scribed by Chin-Hsien Lin; Jiann-Shing Jeng; Ping-Keung Yip

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 299 KB
Volume: 19
Category: Article
ISSN: 0733-2459
DOI: 10.1002/jca.20022

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✦ Synopsis

Abstract

High‐dose corticosteroid administration has been regarded as the main therapy for acute disseminated encephalomyelitis (ADEM). However, some patients with ADEM do not respond well to this treatment. We successfully used plasmapheresis to treat 2 patients who had ADEM. We also compared our patients' symptoms and clinical outcomes to those from previous reports. Plasmapheresis may be indicated not only for severe cases that fail to improve after high‐dose corticosteroid treatment but also for first‐line treatment. Additional large, controlled, double‐blinded trials are needed to clarify the role of plasmapheresis in ADEM. J Clin. Apheresis 19:154–159, 2004. © 2004 Wiley‐Liss, Inc.

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