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Plasmapheresis for hemolytic crisis and impending acute liver failure in Wilson disease

✍ Scribed by Samuel Asfaha; Mohammed Almansori; Uwais Qarni; Klaus S. Gutfreund

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
90 KB
Volume
22
Category
Article
ISSN
0733-2459

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✦ Synopsis

Abstract

Wilsonian crisis is fatal unless copper removal is initiated early and liver transplantation is performed for patients that fulfill criteria for a poor outcome. We report a patient presenting with severe hemolysis and impending acute liver failure that made a rapid recovery with prompt initiation of plasmapheresis and chelation therapy. Rapid copper removal by plasmapheresis alleviated hemolysis and liver injury. A review of the literature was performed examining the use of plasmapheresis and albumin dialysis with continuous veno‐venous hemodialysis or molecular adsorbents and recirculating system. J. Clin. Apheresis, 2007. Β© 2007 Wiley‐Liss, Inc.

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