𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Plasmapheresis: An adjunct to medical management of severe hyperthyroidism

✍ Scribed by Susan S. Braithwaite; Marion H. Brooks; Sonia Collins; Edward W. Bermes

Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
467 KB
Volume
3
Category
Article
ISSN
0733-2459

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✦ Synopsis

A woman with hyperthyroidism and myasthenia gravis developed respiratory failure in association with radiation-induced thyroiditis. Treatment with steroids, propylthiouracil, propranolol, iodine, and plasmapheresis was associated with dramatic reduction in serum triiodothyronine (T3), serum thyroxine (T4), and thyroglobulin levels and prompt recovery of the patient. The medications that this patient received have been shown to cause an abrupt decline in serum T3 levels with little or no effect on the serum T4 concentration. The 56% decline in serum T4 observed in this patient during the first 24 hours of therapy suggests that plasmapheresis may be a useful adjunct to medical therapy in selected patients with severe hyperthyroidism.

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