Plasma uric acid in patients receiving anticonvulsant monotherapy

✍ Scribed by H.A Ring; A.J Heller; W.J Marshall; A.L Johnson; E.H Reynolds

• Book ID: 103932227
• Publisher: Elsevier Science
• Year: 1991
• Tongue: English
• Weight: 379 KB
• Volume: 8
• Category: Article
• ISSN: 0920-1211
• DOI: 10.1016/0920-1211(91)90070-v

✦ Synopsis

In newly diagnosed adult patients with epilepsy followed prospectively on monotherapy, carbamazepine and phenytoin were associated with a fall in plasma uric acid, but sodium valproate and phenobarbitone were associated with a rise in plasma uric acid. The mechanisms and significance of these findings are discussed.