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Plasma total homocysteine measurement by ion-paired reversed-phase hplc with electrochemical detection

✍ Scribed by S. C. Martin; A. C. Hilton; W. A. Bartlett; A. F. Jones

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 35 KB
Volume: 13
Category: Article
ISSN: 0269-3879
DOI: 10.1002/(sici)1099-0801(199902)13:1<81::aid-bmc762>3.0.co;2-u

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✦ Synopsis

Homocysteine is thought to be a risk factor for vascular disease and this has led to an increase in demand for its assay in clinical laboratories. An HPLC method, incorporating electrochemical detection, for measurement of plasma total homocysteine is presented. The method is simple to perform, precise and suitable for clinical applications.

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