Plasma surface modification of artificial corneas for optimal epithelialization

✍ Scribed by Latkany, R. ;Tsuk, A. ;Sheu, M.-S. ;Loh, I.-H. ;Trinkaus-Randall, V.

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 562 KB
• Volume: 36
• Category: Article
• ISSN: 0021-9304
• DOI: 10.1002/(sici)1097-4636(199707)36:1<29::aid-jbm4>3.0.co;2-n

✦ Synopsis

We have demonstrated that the optimal surface results. Organ culture experiments further demonstrated the treatment of a polyvinylalcoholcopolymer hydrogel for epi-efficacy of the argon-treated surfaces. In these experiments, thelial cell migration and proliferation is an argon radio fre-intact keratoprosthetic devices with modified hydrogel surquency (rf) plasma treatment. The surface chemistry of the faces were implanted into rabbit corneas. The excised corneas material was determined prior to each cellular evaluation, containing the devices were cultured, and 3 weeks later, allowing us to compare the biological response with a known using confocal laser scanning microscopy, confluent epithesurface chemistry. The cellular response was carried out in lium was detected on the modified hydrogel surface. This is a consistent manner a minimum of three separate runs. We the first demonstration that rabbit limbal epithelial cells can found that the optimal conditions required culturing the cells migrate onto a synthetic cornea containing a modified hyunder constant rotation. Cells became confluent on argon-drogel-treated surface and form a confluent surface of epitheplasma-treated surfaces coated under several different reac-lium.