✦ LIBER ✦

Plasma profiles of adrenocorticotropic hormone, cortisol, growth hormone and prolactin in patients with untreated parkinson's disease

✍ Scribed by G. Bellomo; L. Santambrogio; M. Fiacconi; A. M. Scarponi; G. Ciuffetti

Publisher: Springer
Year: 1991
Tongue: English
Weight: 382 KB
Volume: 238
Category: Article
ISSN: 0340-5354
DOI: 10.1007/bf00319704

No coin nor oath required. For personal study only.

✦ Synopsis

Plasma profiles of prolactin, growth hormone, adrenocorticotropic hormone (ACTH) and cortisol were evaluated in a group of untreated patients with idiopathic Parkinson's disease and a group of healthy age-matched controls. Plasma integrated concentrations of all hormones except prolactin were significantly lower in the patients as compared with the controls; however, prolactin nocturnal peak concentration was significantly elevated in the patients; nocturnal growth hormone levels were significantly reduced in the Parkinson group; ACTH and cortisol plasma concentrations were also consistently lower during most of the day in the patients with Parkinson's disease. These data confirm the presence of a hypothalamic disturbance in patients with idiopathic Parkinson's disease, which can affect pituitary function.

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