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Plasma persistence of 2-aminothiazoline-4-carboxylic acid in rat system determined by liquid chromatography tandem mass spectrometry

✍ Scribed by Ilona Petrikovics; Jorn C.C. Yu; David E. Thompson; Prashanth Jayanna; Brian A. Logue; Jessica Nasr; Raj K. Bhandari; Steven I. Baskin; Gary Rockwood

Book ID
116620720
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
277 KB
Volume
891-892
Category
Article
ISSN
1873-376X

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## Abstract A method for the quantification of clavulanic acid in calf plasma using high‐performance liquid chromatography combined with electrospray ionization (ESI) mass spectrometry, operating in the negative ionization mode (LC‐MS/MS), is presented. Sample preparation includes a simple and fast