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Plasma N-terminal pro-B-type natriuretic peptide concentration helps to predict survival in dogs with symptomatic degenerative mitral valve disease regardless of and in combination with the initial clinical status at admission

✍ Scribed by François Serres; Jean-Louis Pouchelon; Laure Poujol; Hervé P. Lefebvre; Cathy Trumel; Thomas Daste; Carolina Carlos Sampedrano; Vassiliki Gouni; Renaud Tissier; Gerhard Hawa; Valérie Chetboul


Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
520 KB
Volume
11
Category
Article
ISSN
1760-2734

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✦ Synopsis


Objectives: Although mitral valve disease (MVD) is the most common canine heart disease, readily available prognostic markers of the disease are still lacking. The aim of this study was to evaluate the comparative ability of N-terminal pro-B-type natriuretic peptide plasma concentration (NT-proBNP) and various echocardiographic variables to predict outcome in dogs with MVD. Animals, materials and methods: Seventy-four dogs with ISACHC classes 2 and 3 MVD (Groups A and B, respectively) were prospectively recruited. NT-proBNP and * Corresponding author. Unite ´de Cardiologie d'Alfort, Ecole Nationale Ve ´te ´rinaire d'Alfort, 7 avenue du Ge ´ne ´ral de Gaulle,