Plasma membranes from human liver contain an enzyme activity that removes the membrane anchor of alkaline phosphatase and converts it to a plasma-like form

Human liver plasma membranes contain an

Human liver plasma membranes contain an enzyme activity that removes membrane anchor from alkaline phosphatase and converts it to a plasma-like form

✍ Robert A. Stinson; Brad A. Hamilton 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 763 KB

Treatment of liver plasma membranes with Triton X-100 allowed an endogenous alkaline phosphatase-converting activity to convert amphiphilic alkaline phosphatase (membrane anchor covalantly attached) to hydrophilic dimers that resemble the enzyme found in normal plasma. The Triton-solubilized activit