Plasma membrane proteomic analysis of human osteosarcoma and osteoblastic cells: revealing NDRG1 as a marker for osteosarcoma

Runx2, p53, and pRB status as diagnostic

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1)

✍ Barry P. Pereira; Yefang Zhou; Anurag Gupta; David T. Leong; Khin Zarchi Aung; L 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 503 KB

## Abstract Osteosarcomas are the most prevalent primary bone tumors found in pediatric patients. To understand their molecular etiology, cell culture models are used to define disease mechanisms under controlled conditions. Many osteosarcoma cell lines (e.g., SAOS‐2, U2OS, MG63) are derived from C