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Plasma membrane damage sensing and repairing. Role of heterotrimeric G-proteins and the cytoskeleton

✍ Scribed by Rosa Calvello; Vincenzo Mitolo; Angela Acquafredda; Antonia Cianciulli; Maria Antonietta Panaro

Book ID
116920439
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
576 KB
Volume
25
Category
Article
ISSN
0887-2333

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The ezrin-radixin-moesin (ERM) family of proteins crosslink actin filaments and integral membrane proteins. Radixin (encoded by Rdx) is the dominant ERM protein in the liver of wildtype mice and is concentrated at bile canalicular membranes (BCMs). Here we show that Rdx(؊/؊) mice are normal at birth