The relation of LDL receptor activity to
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Giancarlo Ghiselli; Antonio Gaddi
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Article
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1994
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Elsevier Science
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English
β 415 KB
Elevation of blood cholesterol, low-density lipoproteins (LDL) and apolipoprotein B (apoB) are hallmarks of familial hypercholesterolemia (FH), a genetic condition caused by the defective functioning of the cellular receptor for apoB-100 in LDL. ApoB-100 is also present in lipoprotein(a) (Lp(a)). In