The role of metabolites in valproic acid (VPA)-associated hepatotoxicity was studied in rats. The most steatogenic mono-unsaturated metabolite, 4-en-VPA, caused the greatest changes in indicators of beta-oxidation inhibition (dicarboxylic aciduria, beta-hydroxybutyrate reduction); however, the bioch
✦ LIBER ✦
Plasma levels of valproic acid and its metabolites during continued treatment in dogs
✍ Scribed by W. LÖSCHER
- Book ID
- 114744155
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 517 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0140-7783
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