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Plasma Levels of Interleukin-18 and Interleukin-18 Binding Protein Are Elevated in Patients with Chronic Liver Disease

✍ Scribed by Othmar Ludwiczek; Arthur Kaser; Daniela Novick; Charles A. Dinarello; Menachem Rubinstein; Wolfgang Vogel; Herbert Tilg

Book ID
110397459
Publisher
Springer
Year
2002
Tongue
English
Weight
60 KB
Volume
22
Category
Article
ISSN
0271-9142

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## Background: Interleukin-18 (il-18) is increased in the inflamed mucosa of patients with crohn's disease (cd). the balance between this pleiotropic proinflammatory cytokine and its natural inhibitor, il-18-binding protein (il-18bp), may contribute to the pathogenesis of inflammatory bowel disease